ATP synthase is a ubiquitous, highly conserved enzyme that catalyses the formation of ATP from ADP and P i using a unique rotary motor mechanism. The enzyme is located in the inner membrane of ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans, has ...

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure at 6.2-angstrom ...

研究人员针对高盐环境下叶绿体ATP合酶(ATP synthase)二聚化机制在体功能不明确的问题，通过构建脂质体模型系统，探究了NaCl、NaNO3 和Na2 SO4 等盐离子对酶活性和热稳定性的影响。发现1 M高离子强度可使ATP合成活性降低50%，并使熔解温度从60.5℃升至62.0℃，证实盐 ...

Laura Preiss, Adriana L. Klyszejko, David B. Hicks, Jun Liu, Oliver J. Fackelmayer, Özkan Yildiz, Terry A. Krulwich, Thomas Meier Proceedings of the National Academy of Sciences of the United States ...

Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the formation of ATP ...

Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like ...