Inside nearly every cell of your body, the tiny F1 motor works non-stop to create adenosine triphosphate (ATP), the universal ...

ATP synthase is a ubiquitous, highly conserved enzyme that catalyses the formation of ATP from ADP and P i using a unique rotary motor mechanism. The enzyme is located in the inner membrane of ...

Bonn, January 10, 2023 - Scientists led by Prof. Thomas Becker, Director of the Institute of Biochemistry and Molecular Biology at the University Hospital Bonn (UKB), have gained new insights into the ...

"The ATP synthase protein complex consists of a spinning rotor driven by the back transport of protons into the mitochondrial matrix. This part is connected to the enzyme's catalytic head by a stalk, ...

The chemical ATP, adenosine triphosphate, is the fuel that powers all life. Despite ATP's central role, the structure of the enzyme generating ATP, F1Fo-ATP synthase, in mammals, including humans, has ...

Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered by ...

The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure at 6.2-angstrom ...

ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. Researchers have isolated the machines from four fungal species, compared their stabilities ...

Six structures exhibited by the rotating sodium ion pump were reconstructed in 3D using cryo-electron microscopy. This analysis revealed that (1) the rotor exhibits non-uniform rotation behavior due ...

This is a preview. Log in through your library . Abstract Mitochondria have a characteristic ultrastructure with invaginations of the inner membrane called cristae that contain the protein complexes ...