Figure 1: p53-family-based cell-fate decisions. Figure 2: p53 family functions in myogenic differentiation and in rhabdomyosarcoma. Even in the modern era of cancer genomics, the classic ...
A new machine learning method has achieved what even AlphaFold cannot — the design of intrinsically disordered proteins (IDPs), the shape-shifting biomolecules that make up nearly 30% of all human ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 41 (October 9, 2018), pp. E9630-E9639 (10 pages) Plasma cell differentiation involves coordinated changes ...
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Order from disordered proteins: Physics-based algorithm designs biomolecules with custom ...
In synthetic and structural biology, advances in artificial intelligence have led to an explosion of designing new proteins ...
At the recent European Respiratory Society meeting, researchers from 35Pharma Inc. presented data on HS-235, an activin receptor inhibitor designed to neutralize activins and growth differentiation ...
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