Most sporadic solid tumors require several mutational genetic events prior to acquisition of a malignant phenotype and development of neoplasia. Age-specific incidence data in head and neck squamous ...

The clinical significance of WT1 gene expression at diagnosis and during therapy of AML has not yet been resolved. We analysed WT1 expression at presentation in an unselected group of 47 childhood AML ...

The polymerase chain reaction (PCR), invented about three decades ago, soon entered mainstream use thanks to an ongoing series of refinements. One particularly important refinement, introduced about ...

Real-time PCR or quantitative PCR (Polymerase Chain Reaction) is an advancement of the standard PCR technique, which enables continuous monitoring of the reaction and collection of data in real time.

In recent years, quantitative real-time PCR tests have been extensively developed in clinical microbiology laboratories for routine diagnosis of infectious diseases, particularly bacterial diseases.

Polymerase Chain Reaction (PCR) is a method which utilizes the mechanism of DNA replication to amplify a specific part of DNA. This involves the use of DNA polymerase, which makes new strands of DNA ...

A quantitative, real-time, nested polymerase chain reaction (PCR) method, combining the high sensitivity of nested PCR with time-saving real-time instrumentation, was developed for large-scale ...

Until now, quantitative real-time PCR has been considered to be the gold standard for molecular diagnosis of infectious diseases. Although many laboratories ...

The IntelliQube is a fully integrated liquid handling and real-time quantitative PCR instrument optimized for use with miniaturized reactions in 768-well Array Tape®. The performance characteristics ...