CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage ...

A new tool greatly improves scientists’ ability to identify and study proteins that regulate gene activity in cells, ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

A novel chemo-enzymatic approach to making synthetic 100-unit oligonucleotide single guide RNA (sgRNA) increases both purity and yield, according to its developers at F. Hoffmann-La Roche and ...

Chemists at University College London have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of ...