来自国内的研究人员开发了NAP-seq技术，通过T4 PNK预处理、RNase H去除高丰度RNA、随机条形码接头和热稳定逆转录酶等创新方法，实现了对多种末端修饰的非帽式RNA(napRNAs)的全长单核苷酸分辨率测序，为发现新型调控性非编码RNA和揭示RNA生物合成机制提供了突破性 ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has ...

Researchers have discovered that mice possess a natural form of gene therapy, a non-coding RNA that can sidestep genetic mutations. They were able to engineer a programmable version that recognized ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

Although evolution awarded us with appendages and complex sensory systems, the human body, much like a worm, is simply a large tube transporting food from one end to the other. It is hard to imagine ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

TORINO, Italy--(BUSINESS WIRE)--Resalis Therapeutics today announced its completion of the seed financing round of €10 million to establish a non-coding RNA (ncRNA)-based therapeutic approach for the ...