This review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE).

Objective In 2015, the Department of Health in England announced an ambition to reduce ‘brain injuries occurring during or soon after birth’. We describe the development of a pragmatic case definition ...

Correspondence to Dr Karen M Logan, Section of Neonatal Medicine, Chelsea and Westminster Hospital Campus, Imperial College London, London SW10 9NH, UK; k.logan{at}imperial.ac.uk Objective Maternal ...

Design Prospective follow-up of infants enrolled in randomised controlled trial. Participants 58 infants born before 28 weeks of gestation with low mean arterial blood pressure. Intervention Random ...

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Trial design A randomised, parallel group, pragmatic trial. Setting A large UK maternity hospital. Participants Term infants <2 weeks old with a mild or moderate degree of tongue-tie, and their ...

Background In neonatal trials, verbal opt-out consent has been used to reduce burden on families and make recruitment more efficient and representative. It involves information provision through ...

2 College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK 3 Health and Human Sciences, University of Westminster, London, UK Objectives To investigate the ...

Correspondence to E Sabrina Twilhaar, Clinical Neuropsychology section Vrije Universiteit Amsterdam, Van der Boechorststraat 1, Amsterdam 1081 BT, The Netherlands; e.s.twilhaar{at}vu.nl Background ...

1 Department of Neonatology, Hospital Sant Joan de Déu and Neonatal Brain Group, Institut de Recerca Sant Joan de Déu, Barcelona, Spain Objective To evaluate the association between neuroimaging and ...

Objective To evaluate the implementation of switch from intravenous-to-oral antibiotic therapy with amoxicillin in neonates with early-onset infection (EOI). Design, setting and patients A ...

Setting Eight neonatal units in South Asia. Patients Neonates (≥36 weeks) with moderate or severe HIE admitted between 31 December 2022 and 3 May 2023. Interventions Erythropoietin (500 U/kg daily) or ...