They derive their energy from differences in the concentration of hydrogen ions across some of these membranes ...

ATP has many functions in the body, including neurotransmission, DNA and RNA synthesis, intracellular signaling, and muscle contraction. It can also be used clinically in pain management, anesthesia, ...

Abstract: Endothelial cells (ECs) release ATP in response to shear stress, a mechanical force generated by blood flow, and the ATP released modulates EC functions through activation of purinoceptors.

Abstract The effect of cyclosporin A on induction of nitric oxide synthase in rat aortic smooth muscle cells was examined. A combination of interleukin-1α (100 U/mL) and tumor necrosis factor−α (5000 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. While mechanisms controlling uncoupling ...

Mitochondrial dysfunction is a primary driver of cardiac contractile failure; yet, the cross talk between mitochondrial energetics and signaling regulation remains obscure. Ponatinib, a tyrosine ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Sickle cell disease is a genetic condition affecting at least 100,000 Americans. The U.S. Food and Drug Administration (FDA) on Friday announced that it has approved Casgevy, the first CRISPR ...

A new analysis of more than 1,500 papers and 60 types of tissue has revealed the total number of cells in the human body. When you purchase through links on our site, we may earn an affiliate ...