BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...

USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...

Researchers observed an overall increase in the absolute median cost of the “best available” guideline-concordant treatments for common solid tumor malignancies from 2017 to 2021.

The Coriolis force, a result of Earth’s rotation, significantly influences the movement of the atmosphere and ocean. Despite ...

Background Clinical guidelines recommend pregnant women without contraindication engage in regular physical activity. This is based on extensive evidence demonstrating the safety and benefits of ...

Queerness isn't the main point of these movies, but they've been embraced by the LGBTQ+ community nonetheless.

Severe lymphopenia, an adverse treatment effect associated with chemotherapy, radiotherapy, and immunotherapy, significantly lowers overall survival in non-small cell lung cancer and multiple types of ...

Fungi may have shaped Earth’s landscapes long before plants appeared. By combining rare gene transfers with fossil evidence, researchers have traced fungal origins back nearly a billion years earlier ...

The rate of acquisition of genomic changes in cancer has been the topic of much discussion, with several recent investigations finding evidence of punctuated evolution instead of gradual accumulation ...

Fungi arose long before plants, shaping Earth with early soils and nutrient cycles. Their hidden legacy shows they may have prepared the world for life to flourish on land.