It's no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

This whitepaper highlights a ligation-based workflow that enhances gRNA purity and yield, delivering consistent performance for demanding genome editing applications.

For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...

Chemists at University College London have shown how two of biology's most fundamental ingredients, RNA (ribonucleic acid) and amino acids, could have spontaneously joined together at the origin of ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

SANTA CRUZ — A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, has created an innovative software program called CRISPRware, ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...