PEGASUS generates permeable macrocyclic peptides, offering new promise for a modality that can combine the properties of a biologic in a pill ...

Learn how chain-of-thought and a guided meta-system boosted ChatGPT 5’s abstract thinking, so you can pick better tools for complex tasks.

Hone Health reports that GLP-1 medications are increasingly prescribed for weight loss and metabolic health, even in those ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Optimization problems often involve situations in which the user's goal is to minimize and/or maximize not a single objective function, but several, usually conflicting, functions simultaneously. Such ...

Solving optimization problems is challenging for existing digital computers and even for future quantum hardware. The practical importance of diverse problems, from healthcare to financial ...

Dominik Bošnjak is a freelance writer from Croatia. He has been writing about games for as long as he can remember and began doing so professionally circa 2010. If he was forced to pick a favorite ...

Abstract: This letter addresses distributed nonconvex constrained optimization problems, where both the local cost function and the inequality constraint function are nonconvex. Firstly, the global ...

ENFORCpp is a C++ tool that allows you to solve nonlinear constrained optimization problems. The tool is designed with real-time considerations and is suitable for online trajectory and control input ...

Abstract: This paper addresses a class of optimization problems with time-varying cost functions by proposing a fully distributed prescribed-time algorithm. The algorithm decomposes the overall ...

1 School of Mathematics and Statistics, Fuzhou University, Fuzhou, China. 2 College of Computer and Data Science, Fuzhou University, Fuzhou, China. In this paper, we use Physics-Informed Neural ...