EXPORT MECHANISM: The tRNA must mature inside the nucleus before export. tRNAs are aminoacylated, and only tRNAs charged with an amino acid are exported efficiently. Export occurs when the tRNA is ...

Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.

Scientists have uncovered key new information towards understanding the crucial first step in protein synthesis, the process by which the genetic code, harbored within DNA and copied into RNA, is ...

This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...

Ribosome Assembly: New research shows that neurons not only synthesize proteins locally near synapses. They can also assemble ribosomes at synapses. Dynamic Regulation: Local ribosome maturation ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, No. 8 (Apr. 15, 1987), pp. 2317-2321 (5 pages) The subcellular distribution of v-sis-related protein(s) was ...

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival. Bacteria are no exception, with molecular machines involved in ...

Disease-causing huntingtin, shown in red, interacts with ribosomes, shown in green, in a striatal neuron. The nucleus is blue. [Nicolai Urban of Max Planck Institute for Neuroscience in Jupiter, ...

New research has provided fresh insights into how a dangerous bacterium called Legionella pneumophila can interfere with the normal functions of the cells it infects. The findings have been reported ...

When a bone grows, our bodies’ proteins help provide the structure. When a muscle tears, proteins help rebuild it. When we fight an infection, transport oxygen in our blood or send messages to a cell, ...